Oct 22, 2008

- Imaging techniques in Pathology-

Israel's ASI gives pathologists a vital second opinion - ISRAEL21c

-I have written previously about the subjectivity involved in the practise of Pathology. Its difficult to get two pathologists to agree on any one diagnosis if both pathologists insist on looking at the case through the prism of their own experiences.Besides, it is always tough disputing any one"s diagnosis as it is merely an opinion and reflects the Pathologists own "view" of the case.

Now, ASI (Applied Spectral Imaging), a privately held company in Israel has come up with a colorful solution for the problem. Instead of depending totally on the "morphology", ie shape and size, it provides a way to visualize the antigenic proteins present in the tissue. Using their Spectracube family of products, It allows researchers to distinguish between
different materials on a chromosome by highlighting its features with
unique colors, instead of the black dye that had been used previously. This leads to better identification in suspicious cases and the test also lends itself to reproducibility.

The company has already launched " TB Finder" in the market.In addition to TB Finder, ASI is already selling
or planning to market additional tools for pathologists, including
PathEx, as well as for morphologists, who examine protein structures
and alterations in cell structures.


The company presently promotes its products only as a backup / second opinion. But this seems to be more out of its desire not to rub the so-called "Specialists" the wrong way. Being able to corroborate one"s opinion by a scientific and a reproducible test is a tool sorely needed in the practise of Pathology. I shall not be surprised if such corroboration of opinion of a pathologist soon becomes a norm rather than an option.

All in all, a very very useful service to improve accuracy of diagnosis.

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